| 1. | It reduces blood pressure and peripheral resistance and produces fluid retention.
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| 2. | Peripheral resistance is determined by functional and anatomic changes in small arteries and arterioles.
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| 3. | Many mechanisms have been proposed to account for the rise in peripheral resistance in hypertension.
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| 4. | Exposure to vascular hypertrophy, leading to progressive increases in peripheral resistance and blood pressure.
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| 5. | The drug acts on the renin-angiotensin system to decrease total peripheral resistance in two ways.
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| 6. | Nitric oxide reduces both total peripheral resistance and venous return, thus decreasing both preload and afterload.
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| 7. | This relaxation will decrease total peripheral resistance, which will in turn decrease venous return to the heart.
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| 8. | This will result in a decrease in total peripheral resistance and a decrease in preload on the heart.
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| 9. | Its actions are to increase peripheral resistance via end-tidal CO 2 or E T CO 2 levels.
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| 10. | Vasodilation directly affects the relationship between mean arterial pressure, cardiac output, and total peripheral resistance ( TPR ).
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